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Fertility and Sterility. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} rash. 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. What medications or herbal remedies do you take? Finasteride (Propecia) is a medication that can help treat MPB by lowering levels of DHT. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. After stopping, I got ED, extreme fatigue, brain fog, no libido and lethargy. Metabolism of progesterone and testosterone into 5alpha-reduced metabolites and their mechanisms of action: effects of finasteride and dutasteride. I dont really understand why theyre like that. I dunno, I dont get it. https://old.reddit.com/r/FinasterideSyndrome/comments/psjeuu/could_trying_finasteride_for_1_month_be_harmfull/he38hlf/. Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. Bethesda, MD 20894, Web Policies I'll be interested to see if this has any effects on my weight loss endeavors. Ketamine for treatment-resistant depression: When and where is it safe? To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. My personal experience is that finasteride is an important medication for older guys on TRT that are experiencing BPH. Adverse effects of common medications on male fertility. They claim its more to cover their ass because they dont want people trying whatever unproven solution and get worse and commit suicide or something. Their attitude is 100% there is no cure, it wont get better, nothing works, anything that does work doesnt work long term, and thats just how it is. Around 8 months and i was pretty much recovered. What Causes Hair Loss in Women? There was this guy on propecia help called JustQuitDut who was a complete psycho, who thought that taking TRT with estrogen blockers would somehow solve it. Now and for the past six months, I feel great, my libido is great, mental issues are gone, ED is gone. Examples include bladder neck surgery and transurethral resection of the prostate. Certain medications used to treat retrograde ejaculation can increase your blood pressure and heart rate, which can be dangerous if you have high blood pressure or heart disease. Partin AW, et al., eds. Its less than ideal though when trying to help people and you get banned for it, That forum is a farce, it seems their solution is to just wait, could help for some but others are waiting for years without improving. Brain fog. And posted the article and some cliffs about his solution. Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? WebNeurogenesis was found to be reversed to normal 35 days after the last finasteride injection in male mice. Last time I was on there they had started discussing some relationships between HCG and Thyroid? Pharmaceuticals (Basel). Make a donation. Im on HCG now too though so who knows, maybe itll help too, Powered by Discourse, best viewed with JavaScript enabled, Video: "Is Post Finasteride Syndrome Real? A single copy of these materials may be reprinted for noncommercial personal use only. Health Alerts from Harvard Medical School. Give it 6 months. An official website of the United States government. I had all the classic symptoms. They kept saying it was on the verge of having a major announcement 2 YEARS ago. In addition, it has been also reported that persistent side effects may occur in some AGA patients. 2016;101:46694680. Is there a generic alternative to the medicine you're prescribing me? Wonder if this would work for me? Examine your urine for the presence of semen after you have an orgasm. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. Urology. Even Viagra wouldnt get me hard. 2012;97:306. i am so desperate.. i am a female.. i need my hair back.. but o reallu cannot undergoo all this syntomps ( i gained 20 kg on fina and dutasterde.. no muscle stranght anymore.. no way to lose weight.. i really can' t tell a lot about mental and neurological condition.. but II am so depressed too.. but probably because I am bald and fat there must be a way to take fina without sides.. there must be a way..). Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal Shift work can harm sleep and health: What helps? 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. Stop watching porn, stop masturbating, forget about sex, meditate, take cold showers, try breathing exercises, try extended water fasting. I cycled herbal androgen boosting supplements combined with intense workouts (I am a bodybuilder). Accessed Oct. 28, 2021. Q. I have heard that finasteride, which I take for my prostate problem, can cause permanent impotence. Teeranachaideekul V, Parichatikanond W, Junyaprasert VB, Morakul B. Eliminate Trigger Foods. WebA deterioration in the quality of life in affected individuals does not justify use of the drug. I took a prescription-strength anti-estrogen, Tamoxifen 10mg, twice a day: one at around 3pm and another one together with my test booster before bedtime. Treatment for Post Finasteride Syndrome There is no known treatment of PFS. Drugs generally won't help if retrograde ejaculation is due to surgery that causes permanent physical changes of your anatomy. For each day that goes by, I get a day of surplus inventory. Accessed Sept. 15, 2016. Finasteride blocks the metabolism of testosterone. Since your question stresses on age and since there might be other young people in their 20s and 30s who might find this question and come looking for answers, I thought I might start by pointing that out.  This site needs JavaScript to work properly. Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. Your doctor will ask you questions about your health and symptoms. Melcangi RC, Caruso D, Abbiati F, Giatti S, Calabrese D, Piazza F, Cavaletti G. J Sex Med. Before 2016 Sep;13(9):1297-1310. doi: 10.1016/j.jsxm.2016.07.006. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? I was on TRT when I got PFS. In such cases, treatment depends on the underlying cause. After stopping 7 weeks later (when I ran out of my proviron), things felt off for a few weeks but then after around two months I got back to my pre-PFS state. Federal government websites often end in .gov or .mil. I feel like I have my life back. Finasteride blocks the metabolism of testosterone. If your doctor suspects your dry orgasm is something other than retrograde ejaculation, you might need further tests or a referral to a specialist to find the cause. This area was the most recovery and reversal of symptoms. Studies show it can help slow or reverse the process of hair loss. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Im only able to maintain arousal under very peculiar circumstances, and even thats not the level of hardness Im used to having pre-fin. 2022 Jul 27;15(8):930. doi: 10.3390/ph15080930. Metab. Adverse effects of 5-reductase inhibitors: What do we know, don't know, and need to know? breast tenderness. Firstly, hair loss doesn't just affect older people. J. Clin. The article stated proviron was the best potential cure in his opinion. ._3-SW6hQX6gXK9G4FM74obr{display:inline-block;vertical-align:text-bottom;width:16px;height:16px;font-size:16px;line-height:16px} The data does support that finasteride does have sexual side-effects for guys that are not on TRT while you are using it. The supplement is making real changes in my body and mind, and it feels incredible. 2021 Dec 13;54(4):422-434. doi: 10.1055/s-0041-1739254. HHS Vulnerability Disclosure, Help What is infertility? Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. I haven't had that sort of performance since I was 19 or 20 years old. Check his posts and look at the reasons. "I had a case of PFS that was a severe as it gets. Depending on the likely cause of your dry orgasms and whether you need evaluation and treatment to help you get your female partner pregnant, you might need to see a urinary and reproductive specialist (urologist). In addition, molecular mechanisms and/or genetic determinants behind such adverse effects have been poorly explored both in patients and animal models. The site is secure. FOIA Epub 2013 Jul 24. In: Ferri's Clinical Advisor 2022. Elsevier; 2021. https://www.clinicalkey.com. I recovered and I hope all of you suffering from PFS recover too. there are many options including peptides, and HCG as well as clomid/arimidex. 2016;93:9. Were on our own to beat this, just wait is the worst solution to pfs there is. Should I be concerned? Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. ._3Qx5bBCG_O8wVZee9J-KyJ{border-top:1px solid var(--newCommunityTheme-widgetColors-lineColor);margin-top:16px;padding-top:16px}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN{margin:0;padding:0}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;display:-ms-flexbox;display:flex;-ms-flex-pack:justify;justify-content:space-between;-ms-flex-align:center;align-items:center;margin:8px 0}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ.QgBK4ECuqpeR2umRjYcP2{opacity:.4}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ label{font-size:12px;font-weight:500;line-height:16px;display:-ms-flexbox;display:flex;-ms-flex-align:center;align-items:center}._3Qx5bBCG_O8wVZee9J-KyJ ._2NbKFI9n3wPM76pgfAPEsN ._2btz68cXFBI3RWcfSNwbmJ label svg{fill:currentColor;height:20px;margin-right:4px;width:20px;-ms-flex:0 0 auto;flex:0 0 auto}._3Qx5bBCG_O8wVZee9J-KyJ ._4OtOUaGIjjp2cNJMUxme_{-ms-flex-pack:justify;justify-content:space-between}._3Qx5bBCG_O8wVZee9J-KyJ ._4OtOUaGIjjp2cNJMUxme_ svg{display:inline-block;height:12px;width:12px}._2b2iJtPCDQ6eKanYDf3Jho{-ms-flex:0 0 auto;flex:0 0 auto}._4OtOUaGIjjp2cNJMUxme_{padding:0 12px}._1ra1vBLrjtHjhYDZ_gOy8F{font-family:Noto Sans,Arial,sans-serif;font-size:12px;letter-spacing:unset;line-height:16px;text-transform:unset;--textColor:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColor);--textColorHover:var(--newCommunityTheme-widgetColors-sidebarWidgetTextColorShaded80);font-size:10px;font-weight:700;letter-spacing:.5px;line-height:12px;text-transform:uppercase;color:var(--textColor);fill:var(--textColor);opacity:1}._1ra1vBLrjtHjhYDZ_gOy8F._2UlgIO1LIFVpT30ItAtPfb{--textColor:var(--newRedditTheme-widgetColors-sidebarWidgetTextColor);--textColorHover:var(--newRedditTheme-widgetColors-sidebarWidgetTextColorShaded80)}._1ra1vBLrjtHjhYDZ_gOy8F:active,._1ra1vBLrjtHjhYDZ_gOy8F:hover{color:var(--textColorHover);fill:var(--textColorHover)}._1ra1vBLrjtHjhYDZ_gOy8F:disabled,._1ra1vBLrjtHjhYDZ_gOy8F[data-disabled],._1ra1vBLrjtHjhYDZ_gOy8F[disabled]{opacity:.5;cursor:not-allowed}._3a4fkgD25f5G-b0Y8wVIBe{margin-right:8px} Almost starting to think like a conspiracy theorist. To diagnose retrograde ejaculation, your doctor may: If you have dry orgasms, but your doctor doesn't find semen in your bladder, you might have a problem with semen production. If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. This is a condition characterized by an enlarged prostate. This content does not have an Arabic version. Long term HCG treatment at high dosages can cause issues. 8600 Rockville Pike Lol, now they banned me, just look at the reason: Dismissive of survey in first few posts; insistently advocated for dangerous and misleading article on PFS. Feeling low-grade depression constantly. 2019;16 doi: 10.3390/ijerph16101726. This condition, termed post-finasteride syndrome (PFS) is characterized by sexual side effects (i.e., low libido, erectile dysfunction, decreased arousal and difficulty in achieving orgasm), depression, anxiety and cognitive complaints that are still present despite drug withdrawal. WebIn addition to the sexual, mental and physical side effects, PK suffers from miscellaneous issues connected with PFS. Int. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. This report will provide you with the information you need to understand the current controversies, avoid common pitfalls, and work with your doctor to make informed choices about your prostate health. If you have retrograde ejaculation, you'll likely need treatment to get your female partner pregnant. Epub 2022 Feb 3. That's one of the mildest forms of PFS you can experience. Next to no sensitivity in my genitals. No interest in sex at all. Sometimes, more-advanced assisted reproductive techniques are needed. But on day 3, I felt like my old self. Do you and your partner want to have a baby? ._38lwnrIpIyqxDfAF1iwhcV{background-color:var(--newCommunityTheme-widgetColors-lineColor);border:none;height:1px;margin:16px 0}._37coyt0h8ryIQubA7RHmUc{margin-top:12px;padding-top:12px}._2XJvPvYIEYtcS4ORsDXwa3,._2Vkdik1Q8k0lBEhhA_lRKE,.icon._2Vkdik1Q8k0lBEhhA_lRKE{border-radius:100%;box-sizing:border-box;-ms-flex:none;flex:none;margin-right:8px}._2Vkdik1Q8k0lBEhhA_lRKE,.icon._2Vkdik1Q8k0lBEhhA_lRKE{background-position:50%;background-repeat:no-repeat;background-size:100%;height:54px;width:54px;font-size:54px;line-height:54px}._2Vkdik1Q8k0lBEhhA_lRKE._1uo2TG25LvAJS3bl-u72J4,.icon._2Vkdik1Q8k0lBEhhA_lRKE._1uo2TG25LvAJS3bl-u72J4{filter:blur()}.eGjjbHtkgFc-SYka3LM3M,.icon.eGjjbHtkgFc-SYka3LM3M{border-radius:100%;box-sizing:border-box;-ms-flex:none;flex:none;margin-right:8px;background-position:50%;background-repeat:no-repeat;background-size:100%;height:36px;width:36px}.eGjjbHtkgFc-SYka3LM3M._1uo2TG25LvAJS3bl-u72J4,.icon.eGjjbHtkgFc-SYka3LM3M._1uo2TG25LvAJS3bl-u72J4{filter:blur()}._3nzVPnRRnrls4DOXO_I0fn{margin:auto 0 auto auto;padding-top:10px;vertical-align:middle}._3nzVPnRRnrls4DOXO_I0fn ._1LAmcxBaaqShJsi8RNT-Vp i{color:unset}._2bWoGvMqVhMWwhp4Pgt4LP{margin:16px 0;font-size:12px;font-weight:400;line-height:16px}.icon.tWeTbHFf02PguTEonwJD0{margin-right:4px;vertical-align:top}._2AbGMsrZJPHrLm9e-oyW1E{width:180px;text-align:center}.icon._1cB7-TWJtfCxXAqqeyVb2q{cursor:pointer;margin-left:6px;height:14px;fill:#dadada;font-size:12px;vertical-align:middle}.hpxKmfWP2ZiwdKaWpefMn{background-color:var(--newCommunityTheme-active);background-size:cover;background-image:var(--newCommunityTheme-banner-backgroundImage);background-position-y:center;background-position-x:center;background-repeat:no-repeat;border-radius:3px 3px 0 0;height:34px;margin:-12px -12px 10px}._20Kb6TX_CdnePoT8iEsls6{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;margin-bottom:8px}._20Kb6TX_CdnePoT8iEsls6>*{display:inline-block;vertical-align:middle}.t9oUK2WY0d28lhLAh3N5q{margin-top:-23px}._2KqgQ5WzoQRJqjjoznu22o{display:inline-block;-ms-flex-negative:0;flex-shrink:0;position:relative}._2D7eYuDY6cYGtybECmsxvE{-ms-flex:1 1 auto;flex:1 1 auto;overflow:hidden;text-overflow:ellipsis}._2D7eYuDY6cYGtybECmsxvE:hover{text-decoration:underline}._19bCWnxeTjqzBElWZfIlJb{font-size:16px;font-weight:500;line-height:20px;display:inline-block}._2TC7AdkcuxFIFKRO_VWis8{margin-left:10px;margin-top:30px}._2TC7AdkcuxFIFKRO_VWis8._35WVFxUni5zeFkPk7O4iiB{margin-top:35px}._1LAmcxBaaqShJsi8RNT-Vp{padding:0 2px 0 4px;vertical-align:middle}._2BY2-wxSbNFYqAy98jWyTC{margin-top:10px}._3sGbDVmLJd_8OV8Kfl7dVv{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:21px;margin-top:8px;word-wrap:break-word}._1qiHDKK74j6hUNxM0p9ZIp{margin-top:12px}.Jy6FIGP1NvWbVjQZN7FHA,._326PJFFRv8chYfOlaEYmGt,._1eMniuqQCoYf3kOpyx83Jj,._1cDoUuVvel5B1n5wa3K507{-ms-flex-pack:center;justify-content:center;margin-top:12px;width:100%}._1eMniuqQCoYf3kOpyx83Jj{margin-bottom:8px}._2_w8DCFR-DCxgxlP1SGNq5{margin-right:4px;vertical-align:middle}._1aS-wQ7rpbcxKT0d5kjrbh{border-radius:4px;display:inline-block;padding:4px}._2cn386lOe1A_DTmBUA-qSM{border-top:1px solid var(--newCommunityTheme-widgetColors-lineColor);margin-top:10px}._2Zdkj7cQEO3zSGHGK2XnZv{display:inline-block}.wzFxUZxKK8HkWiEhs0tyE{font-size:12px;font-weight:700;line-height:16px;color:var(--newCommunityTheme-button);cursor:pointer;text-align:left;margin-top:2px}._3R24jLERJTaoRbM_vYd9v0._3R24jLERJTaoRbM_vYd9v0._3R24jLERJTaoRbM_vYd9v0{display:none}.yobE-ux_T1smVDcFMMKFv{font-size:16px;font-weight:500;line-height:20px}._1vPW2g721nsu89X6ojahiX{margin-top:12px}._pTJqhLm_UAXS5SZtLPKd{text-transform:none} At some point you just cant store it all or want to use old drug. While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. Toxicol. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. The Baylor study STILL hasnt been released? My life is finally back. Anejaculation and retrograde ejaculation. They have some pretty smart people and are open to trying about anything, and isnt as negative as the other forum. Write down any symptoms you're experiencing, including any that might seem unrelated to the reason for which you scheduled the appointment. Or at the very least allow people to post ideas. The mods on that forum are fascists and dont allow the opinion and theory of other people. Here's some information to help you get ready for your appointment, and what to expect from your doctor. Personally, I believe its become the boogeyman for a bucket list of sexual problems. This after having PFS constantly for 11 years. When seeing your doctor for dry ejaculation the primary sign of retrograde ejaculation some basic questions to ask your doctor include: If you're trying to get your female partner pregnant, you might also want to ask: In addition to the questions that you've prepared to ask your doctor, don't hesitate to ask additional questions during your appointment. Unauthorized use of these marks is strictly prohibited. I had a case of PFS that was a severe as it gets. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. This can be caused by damage to the prostate or semen-producing glands as a result of surgery or radiation treatment for cancer in the pelvic area. @keyframes ibDwUVR1CAykturOgqOS5{0%{transform:rotate(0deg)}to{transform:rotate(1turn)}}._3LwT7hgGcSjmJ7ng7drAuq{--sizePx:0;font-size:4px;position:relative;text-indent:-9999em;border-radius:50%;border:4px solid var(--newCommunityTheme-bodyTextAlpha20);border-left-color:var(--newCommunityTheme-body);transform:translateZ(0);animation:ibDwUVR1CAykturOgqOS5 1.1s linear infinite}._3LwT7hgGcSjmJ7ng7drAuq,._3LwT7hgGcSjmJ7ng7drAuq:after{width:var(--sizePx);height:var(--sizePx)}._3LwT7hgGcSjmJ7ng7drAuq:after{border-radius:50%}._3LwT7hgGcSjmJ7ng7drAuq._2qr28EeyPvBWAsPKl-KuWN{margin:0 auto} I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. Better to learn the cause of PFS and create a cure based on that. That's far from severe. It is available as a generic. Yeah, yeah. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Ejaculation and orgasm disorders. Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML. Its like they want to hide possible solutions. Thanks for visiting. The information on RealSelf is intended for educational purposes only. I feel deeply for all my balding brothers out there who are suffering from this poison. Drugs that can cause retrograde ejaculation include certain medications for depression and alpha blockers drugs used to treat high blood pressure and some prostate conditions. Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in reading time: 43 12th ed. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. Metabolism of progesterone and testosterone, Metabolism of progesterone and testosterone into 5alpha-reduced metabolites and their mechanisms of action:, Clinical features reported in patients affected by post-finasteride syndrome. In: Campbell-Walsh-Wein Urology. I took intramuscular injections of HCG every 3 a 5 days 1500 to 3000 ui by injections for 1 months only, and after that some Clomid for 10 days 2 pills by day It helped relaunch the natural testorene levels so my libido increased again i am now totally satisfied with my health :slight_smile: https://forum.propeciahelp.com/t/i-believe-i-have-been-cured-by-accident/4054, Yes After nearly 4 years of suffering, I have finally & fully recovered from Post Finasteride Syndrome, All my symptoms have subsided and improved with this method which takes a while but I am fully functional. official website and that any information you provide is encrypted WebPost finasteride syndrome is real. Endocrinol. Next steps is likely getting a Hey there, Effect of 5-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials. (photo). I read the thing on Healthline where it says it doesn't raise testosterone in humans. This procedure is usually done at the doctor's office. Speaking of which the proviron I ordered over a year ago randomly came in the mail the other day, haha. More than a primer on prostate conditions, this Special Health Report, the Annual Report on Prostate Diseases, includes roundtable discussions with experts at the forefront of prostate research, interviews with men about their treatment decisions, and the latest thinking on complementary therapies.